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Hypersensitivity to any of the active substances or to any of the excipients in formulation.
Hypersensitivity to other sulfonamide-derived substances (since hydrochlorothiazide is a sulfonamide-derived medicinal product).
Second and third trimester of pregnancy.
Cholestasis and biliary obstructive disorders.
Severe hepatic impairment.
Severe renal impairment (creatinine clearance <30ml/min).
Refractory hypokalaemia, hypercalcaemia.
The concomitant use of telmisartan with aliskiren is contraindicated in patients with diabetes mellitus or renal impairment (GFR<60ml/min/1.74m2).
